Cat. No.
MABL-3199
Application
ELISA, FC, IHC
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
ABDD073
From
Recombinant Antibody
Specificity
The antibody is specific for VEGFR-3.
Alternative Names
FLT-4; Vascular endothelial growth factor receptor 3; EC:2.7.10.1; Fms- like tyrosine kinase 4; Tyrosine-protein kinase receptor FLT4
UniProt
P35916
Immunogen
The original antibody was generated by immunizing BALB/C mice with VEGFR-3/Ig recombinant protein.
Application Notes
The antibody showed neutralizing activity by ELISA analysis. The antibody detected VEGFR-3 from HEL cell lysates by western blot analysis. The antibody could recognize VEGRF-3 on fetal heart, fetal kidney and fetal lung tissue by immunohistochemistry. The binding activity of the antibody to VEGFR-3 expressed on the surface of HEL cells was confirmed by FACS flow cytometry. In vitro experiments showed the antibody could block the interaction between VEGFR-3 and VEGF-D. The antibody could inhibit HEL cell proliferation. The antibody could inhibit the generation of chicken embryo allantoic membrane blood vessels induced by recombinant GST-VEGF-D (CN1800373A).
Antibody First Published
Note on publication
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
