Key features and details | |
Cat. No. | MABL-1164 |
Name | Anti-CD96 mAbs |
Clone No. | AFD- h1722-010 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | SPR, ELISA |
Species Reactivity | Cynomolgus Macaque, Human |
Basic Information | |
Specificity | This antibody is specific for Human CD96 but cross-reacts with Monkey CD96. |
Alternative Name | Tactile; T cell activation, increased late expression; Cluster of Differentiation 96 |
UniProt | P40200 |
Immunogen | The original antibody was generated by humanizing the anti-CD96 murine antibody clone "m1722". |
Application Notes | In an ELISA assay, this antibody demonstrated an EC50 of 0.073 nM and 0.047 nM against human CD96 and cynomolgus CD96, respectively. In another ELISA, this antibody demonstrated the ability to specifically bind to CD96 overexpressing CHO-S cells with an EC50 of 0.047 nM. Via SPR, the antibody demonstrated an affinity of 0.86 nM to Human CD96. A competitive ELISA assay indicated that this antibody does not compete with Ab04853 Anti-CD96 [ch1720], indicating they target different epitopes. |
Antibody First Published | |
Note on publication | |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |