Key features and details | |
Cat. No. | MABL-1165 |
Name | Anti-CD98 mAbs |
Clone No. | AFD- 18-2a 7.1 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | FACS, SPR |
Species Reactivity | Human |
Basic Information | |
Specificity | The antibody is specific for CD98. |
Alternative Name | LAT1; E16; MPE16; SLC7A5 |
UniProt | Q01650 |
Immunogen | The original antibody was generated by immunizing male 129S6/SvEv mice with human CD98 (huCD98)-expressing tumor cells. |
Application Notes | Binding affinities of the murine and chimeric version of the antibody were determined using FACS analysis (Kd values between 0.9 nM and 4.5 nM). The chimeric antibody was also subjected to FACS analysis using three AML primary tumor samples and one cell line expressing cynomolgus monkey CD98 (cynCD98). The results demonstrated that the chimeric retained binding to human CD98 on AML cells and on cynCD98. The binding affinity of the murine, chimeric and humanized version of the antibody to CD98 was measured by surface plasmon resonance (JP2015501639A5). |
Antibody First Published | |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
