Key features and details | |
Cat. No. | MABL-1767 |
Name | Anti-HA mAbs |
Clone No. | AFD- 310-18A3 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | BLI, ELISA |
Species Reactivity | H5N1 Influenza A Virus |
Basic Information | |
Specificity | This antibody is specific for the H5N1 and H1N1 subtypes of influenza A virus. Influenza viruses are negative-sense, single-stranded, segmented RNA viruses. |
Alternative Name | Hemagglutinin; Avian Influenza Virus; AIV; H5N1; Influenza virus |
UniProt | A5A5M5 |
Immunogen | This antibody was raised by cloning antibody sequences form B cells isolated from people immunized with the H5 DNA vaccine. |
Application Notes | The affinity of this antibody to H1/1999 HA was assessed. This was done by using the human version of this antibody for Bio-Layer Interferometry on H1/1999 HA. Further, an ELISA was preformed using the human version of this antibody on HA from influenza (Whittle et al, 2014; pmid:24501410). |
Antibody First Published | Whittle et al. Flow cytometry reveals that H5N1 vaccination elicits cross- reactive stem-directed antibodies from multiple Ig heavy-chain lineages. J Virol. 2014 Apr;88(8):4047-57. PMID:24501410 |
Note on publication | Structure-based modification of HA to isolate HA-specific B cells by flow cytometry was used and characterize the features of HA stem antibodies (Abs) required for their development. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
