Key features and details | |
Cat. No. | MABL-1853 |
Name | Anti-HLA-A2 mAbs |
Clone No. | AFD- SN66E3 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | FC |
Species Reactivity | Human |
Basic Information | |
Specificity | The antibody specifically binds a determinant shared by human HLA-A2 and A28, but does not cross react with Aw68, or Aw69 antigens. |
Alternative Name | HLA-A; Human leukocyte antigen A; HLA class I histocompatibility antigen; A-2 alpha chain; MHC class I antigen A-2 HLA-A; HLA class I histocompatibility antigen A-28 alpha chain; HLA class I histocompatibility antigen; A-28 alpha chain; MHC class I antigen A-28 |
UniProt | P04439 |
Immunogen | The original antibody was generated from the peripheral B lymphocytes from a multiparous female (SN) who had developed anti-HLA-A2 and anti-HLA-B17 Abs following two pregnancies mismatched for these HLA class I allospecificities. |
Application Notes | This antibody was used in the flow cytometric analysis of HLA class I antigen expression levels on Lymphoblastoid cell lines and class I deficient mutant cells (PMID: 9820600). |
Antibody First Published | Mulder et al. A human monoclonal antibody, produced following in vitro immunization, recognizing an epitope shared by HLA-A2 subtypes and HLA-A28. Tissue Antigens. 1993 Jul;42(1):27-34. PMID:7504327 |
Note on publication | Describes the generation and characterization of antibody against HLA-A2 and HLA- A28. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
