Key features and details | |
Cat. No. | MABL-2115 |
Name | Anti-IL-8RB mAbs |
Clone No. | AFD- HC2 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | FC |
Species Reactivity | Human |
Basic Information | |
Specificity | HC2 recognizes human C-X-C chemokine receptor type 2, (CXCR2). CD182 is a 360 amino acid multipass membrane glcycoprotein and is expressed by neutrophils and monocytes, as well as by some subsets of T cells and endothelial cells. |
Alternative Name | CXCR-2; CD182; C-X-C chemokine receptor type 2; CXC-R2; CXCR-2; GRO/MGSA receptor; High affinity interleukin-8 receptor B; IL-8R B; IL-8 receptor type 2 |
UniProt | P25025 |
Immunogen | This antibody was raised by immunizing mice with human IL-8 (interleukin-8) receptor, type B. |
Application Notes | This antibody can be used in the detection and analysis of IL-8RB via flow cytometry (Zahn et al., 1997). |
Antibody First Published | Zahn et al. Chemoattractant receptors for interleukin-8 and C5a: expression on peripheral blood leukocytes and differential regulation on HL-60 and AML-193 cells by vitamin D3 and all- trans retinoic acid. Eur J Immunol. 1997 Apr;27(4):935-40. PMID:9130647 |
Note on publication | This article describes the generation and characterization of HC2 antibody. |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |