Anti-IL-9 mAbs

Cat. No.

MABL-2116

Name

Anti-IL-9 mAbs

Clone No.

AFD- D9302C12

From

Recombinant Antibody

Isotype

Engineer antibody

Application

Blocking, FC

Species Reactivity

Mouse

Basic Information

Specificity

This antibody is specific for murine IL-9.

Alternative Name

Interleukin-9; IL9; Cytokine P40; T-cell growth factor P40

UniProt

P15247

Immunogen

This antibody was raised by immunising Armenian   hamsters with Baculovirus-expressed, recombinant murine IL-9.

Application Notes

In vitro, this antibody has inhibitory   effects on IL-9 bioactivity, and inhibits the differentiation of Th17 cells   and consequent production of IL-17 (Li et al, 2010). This antibody is also   able to neutralise IL-9 in vivo (Li et al, 2010). Administration of this   antibody suppresses acute experimental autoimmune encephalomyelitis (EAE),   with an observed reduction in MOG-specific Th1 and Th17 cells in the   periphery and the CNS (Li et al, 2010).

Antibody First   Published

Renauld et al. Interleukin‐9 and its   receptor: involvement in mast cell differentiation and T cell oncogenesis J   Leukoc Biol. 1995 57(3):353-60 PMID:7884304

Note on publication

Describes the original generation of this   antibody.

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage   Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.