Key features and details | |
Cat. No. | MABL-2163 |
Name | Anti-Interferon gamma mAbs |
Clone No. | AFD- XMG1.2 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | Blocking, in vivo, neutralization, ELISA, FC |
Species Reactivity | Mouse |
Basic Information | |
Specificity | This antibody is specific for mouse interferon gamma. |
Alternative Name | IFN gamma; IFN-gamma; interferon-γ; IFN-γ; IFNG; IFG; IFI; IMD69 |
UniProt | P01580 |
Immunogen | The original antibody was generated by immunizing a Lewis rat with soluble recombinant mouse IFN-γ. |
Application Notes | The original antibody (rat IgG1, κ) was effective in both ELISA and two blocking bioassays (Cherwinski et al., 1987; PMID: 2960769). This antibody was used successfully in flow cytometry (Sander et al., 1993; PMID: 8288874). This antibody was used in vivo to block and neutralize IFN-γ (Suzuki and Joh, 1994; PMID: 8202451) (Beatty and Paterson, 2001; PMID: 11160282). |
Antibody First Published | Cherwinski et al. Two types of mouse helper T cell clone. III. Further differences in lymphokine synthesis between Th1 and Th2 clones revealed by RNA hybridization, functionally monospecific bioassays, and monoclonal antibodies. J Exp Med. 1987 Nov 1;166(5):1229-44. doi: 10.1084/jem.166.5.1229 PMID:2960769 |
Note on publication | The original publication explores the lymphokine synthesis patterns of T cell clones, distinguishing between two types (Th1 and Th2) based on mRNA hybridization, revealing differences in the production of specific cytokines and providing insights into the functional specificity of these clones using monoclonal antibodies and bioassays. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
