Key features and details | |
Cat. No. | MABL-2352 |
Name | Anti-Metarhodopsin-I mAbs |
Clone No. | AFD- K42-IL |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ELISA |
Species Reactivity | Bovine |
Basic Information | |
Specificity | The antibody binds specifically to the C3-loop of metarhodpsin-I with a Kd of 2.8 nM, the epitope being TGALQERSK. |
Alternative Name | |
UniProt | P02699 |
Immunogen | Bovine rod cell disc membranes. |
Application Notes | This antibody specifically binds to the C3-loop of metarhodopsin-I, which is in equilibrium with the meta-active metarhodopsin II. The antibody stabilises the inactive metarhodopsin-I, inhibiting G-protein activation. |
Antibody First Published | Adamus et al. Use of peptides to select for anti-rhodopsin antibodies with desired amino acid sequence specificities. Peptide Research 1988; 1(1):42-47 PMID:2485225 |
Note on publication | Describes the generation of several monoclonal antibodies against rhodopsin using peptides for hybridoma selection. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
