Key features and details | |
Cat. No. | MABL-2369 |
Name | Anti-MHC II mAbs |
Clone No. | AFD- A6-61.3 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | radioimmunoassay |
Species Reactivity | Mouse |
Basic Information | |
Specificity | This antibody is specific for murine I-A, haplotypes H-2k, d and q. It binds to the β-chain of murine Ia. |
Alternative Name | A6.61.3; I-A; Ia; I-E; MHC-II; MHC Class II |
UniProt | |
Immunogen | This antibody was obtained from a fusion of the non-producing plasmacytoma Ag8.653 with spleen cells from ATL mice that had been immunized with ATH spleen cells. |
Application Notes | This antibody has been used in a cellular radioimmunoassay to investigate the effect of IFN-y treatment on cell surface expression of Ia (Graf et al, 1985). |
Antibody First Published | Koch et al Ia antigens and associated invariant chain are induced simultaneously in lines of T-dependent mast cells by recombinant interferon-gamma. J Immunol. 1984 Mar;132(3):1361-9. PMID:6420464 |
Note on publication | Describes the original generation and characterisation of this antibody. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
