Key features and details | |
Cat. No. | MABL-2641 |
Name | Anti-PD-1 mAbs |
Clone No. | AFD- PD1-28 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | functional assay, Block, ELISA |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody is specific for PD-1. |
Alternative Name | CD279; Programmed cell death protein 1; PDCD1; PD-1; hPD-1 |
UniProt | Q15116 |
Immunogen | The original antibody was generated by panning against an scFv phagemid library generated from non-immunized human donors. |
Application Notes | An ELISA was performed on PD-1 fusion protein using this antibody (US7488802). This antibody was capable of blocking the PD-1/PD-L1 interaction. It was found that PD1-28 can mimic PD-1 ligands and deliver an inhibitory signal causing a decrease in T cell proliferation and IL-2 production (US7488802). |
Antibody First Published | Collins et al. Antibodies against PD-1. US7488802 |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
