Anti-Terminal Deoxynucleotidyl Transferase mAbs

Cat. No.

MABL-3027

Name

Anti-Terminal Deoxynucleotidyl Transferase mAbs

Clone No.

AFD- 32D5

From

Recombinant Antibody

Isotype

Engineer antibody

Application

WB, ELISA, IHC

Species Reactivity

Human

Basic Information

Specificity

The antibody is specific for TdT. TdT   catalyzes the random addition of deoxynucleoside 5'- triphosphate to the   3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the   addition of nucleotides at the junction (N region) of rearranged Ig heavy   chain and T-cell receptor gene segments during the maturation of B- and   T-cells.

Alternative Name

TdT; DNA nucleotidylexotransferase; Terminal addition enzyme; Terminal deoxynucleotidyltransferase; Terminal transferase;   CGMCC NO 20777

UniProt

P04053

Immunogen

The original antibody was generated by   immunizing mice with the recombinant TdT protein.

Application Notes

The antibody specifically detected TDT protein in Western blot analysis. The antibody 32D5 and the commercial   antibody SEN28 were used to stain lymphoma and thymus. Results showed the   antibody specificity is comparable to the commercial antibody. Further, the sensitivity of the antibody 32D5 was higher than the commercial antibody. The   antibody and the commercially available antibody TA347 were simultaneously detected on the normal tissue chip, indicating that the specificity of the   antibody in normal tissue was equivalent to that of the commercially available antibody (CN113265003A).

Antibody First   Published

Note on publication

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage   Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.