Key features and details | |
Cat. No. | MABL-399 |
Name | Anti-Amoxicillin mAbs |
Clone No. | AFD- AbAb-Amox |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ELISA |
Species Reactivity | Species independent |
Basic Information | |
Specificity | This antibody shows reactivity with anhydrous amoxicillin and other penicillin drugs like oxacillin sodium salt monohydrate (OXC), carbencillin disodium salt (CBC), penicillin G potassium salt (PCG), sulbenicillin (SBC), nafcillin sodium salt monohydrate (NFC), cloxacillin sodium salt monohydrate (CLC), penicillin V potassium salt (PCV), methicillin (MTC), APCampicillin trihydrate sodium salt (APC) and dicloxacillin sodium salt monohydrate (DCLC). Amoxicillin is a penicillin antibiotic used to treat bacterial infections such as tonsillitis, bronchitis, sinusitis, pneumonia, and infections of the ear, nose, throat, skin, or urinary tract. |
Alternative Name | AX; Amoxycillin; Amox; ChEBI; 2676 |
UniProt | |
Immunogen | The original antibody was generated by immunizing BALB/c mice with amoxicillin covalently conjugated with BSA. |
Application Notes | The ability of this antibody to bind amoxicillin and other penicillin drugs was determined by ELISA. This antibody shows reactivity with amoxicillin and 10 other penicillin drugs having a common core structure (6-aminopenicilanic acid, APA) and different light chains. The antibody recognized 11 penicillin drugs with an IC50 between 8.5–54.1 ng/mL (PMID 27383141). |
Antibody First Published | Liu J et al. Production of anti-amoxicillin ScFv antibody and simulation studying its molecular recognition mechanism for penicillins. J Environ Sci Health B. 2016 Nov;51(11) (PMID: 27383141). |
Note on publication | Describes the generation of this antibody and investigates its intermolecular interactions with 11 penicillins using molecular docking. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
