Anti-C3a-receptor mAbs

Cat. No.

MABL-570

Name

Anti-C3a-receptor mAbs

Clone No.

AFD- 3G7

From

Recombinant Antibody

Isotype

Engineer antibody

Application

ELISA, FC

Species Reactivity

Human

Basic Information

Specificity

Binds specifically to the 2e loop of the   human C3a receptor, residues 185-193.

Alternative Name

Complement component receptor 1; C3AR1

UniProt

Q16581

Immunogen

The 2e loop of the C3a receptor.

Application Notes

This scFv antibody binds to the 2e loop of   the human C3a receptor, a G protein- coupled receptor stimulating chemotaxis, superoxide anion generation and granule enzyme release.

Antibody First Published

Hawlisch et al. 2001 Site-specific anti-C3a  receptor single-chain antibodies selectied by differential panning on   cellulosesheets. Analytica Biochemistry 2001; 293(1)：142-145 PMID：11373092

Note on publication

Describes the selection of scFv fragments   with specificity for the C3a receptor from phage-display libraries.

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity purified

Buffer

PBS with 0.02% Proclin 300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3 months. For   longer storage, aliquot and store at - 20⁰C.