Name
FXYD5 Human
Cat. No.
MAG-6186
Tag/Conjugates
His
Source
E.coli.
Shipped
Shipped with Ice Packs
Description
FXYD5 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 147 amino acids (22-145 a.a) and having a molecular mass of 16.1kDa. FXYD5 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Synonyms
DYSAD, HSPC113, IWU1, KCT1, OIT2, PRO6241, RIC, FXYD domain-containing ion transport regulator 5, Dysadherin, FXYD5, Keratinocytes Associated Transmembrane Protein 1.
Introduction
FXYD domain-containing ion transport regulator 5 (FXYD5) is a cancer-associated cell membrane glycoprotein which is a part of the FXYD family. FXYD5 is engaged in down-regulation of E-cadherin, which takes part in tumor development and metastasis and results in reduced cell adhesion.FXYD is found in spleen, lung, skeletal muscle, and testis tissue, and maps to human chromosome 19q13.2.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
FXYD5 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.1M NaCl, 10% glycerol and 1mM DTT.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Purity
Greater than 95% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGS QTLKDTT SSSSADSTIM DIQVPTRAPD AVYTELQPTS PTPTWPADET PQPQTQTQQL EGTDGPLVTD PETHKSTKAA HPTDDTTTLS ERPSPSTDVQ TDPQTLKPSG FHEDDPFFYD EHTLRKR.
Safety Data Sheet
SDS
Usage
Mabioway's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
