Name
SERPINA9 Mouse
Cat. No.
MAG-7018
Tag/Conjugates
His
Source
Sf9,
Baculovirus cells.
Shipped
Shipped with Ice Packs
Description
SERPINA9 Mouse Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 401 amino acids (26-418 a.a) and having a molecular mass of 45.2kDa (Molecular size on SDS-PAGE will appear at approximately 50-70kDa). SERPINA9 is fused to an 8 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques.
Synonyms
Serpin A9, Serpina9, SERPINA9.
Introduction
Serpin Peptidase Inhibitor, Clade A
Member 9, also known as serpin A9, belongs to the Serpin superfamily of serine
protease inhibitors. Serpins are the most extensively distributed superfamily
of protease inhibitors which use a conformational modification to inhibit
target enzymes. Serpins are known to inhibit serine proteases as well as
inhibiting caspases in addition to papain-like cysteine proteases. Serpins are
conformational labile and numerous of the disease-linked mutations of serpins
outcome in misfolding or in pathogenic, inactive polymers. serpin A9
demonstrates inhibition towards trypsin, thrombin, as well as plasmin and binds
DNA and heparin.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
SERPINA9 protein solution (0.25mg/ml) contains Phosphate
Buffered Saline (pH 7.4) and 10% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Purity
Greater
than 85.0% as determined by SDS-PAGE.
Amino acid sequence
NPYNQESSHL PSMKKNPASQ VSPSNTRFSF LLYQRLAQEN PGQNILFSPV
SISTSLAMLS LGARSATKTQ ILRTLGFNFT WVSEPTIHMG FEYLVRSLNK CHQGRELRMG SVLFIRKELQ
LQATFLDRVK KLYGAKVFSE DFSNAATAQA QINSYVEKET KGKVVDVIQD LDSQTAMVLV NHIFFKANWT QPFSTANTNK SFPFLLSKGT TVHVPMMHQT ESFAFGVDKE
LGCSILQMDY RGDAVAFFVL PGKGKMRQLE KSLSARRLRK WSRSLQKRWI KVFIPKFSIS ASYNLETILP
KMGIRDAFNS NADFSGITKT HFLQVSKAAH KAVLDVSEEG TEAAAATTTK LIVRSRDTPS SIIAFKEPFL ILLLDKNTES
VLFLGKVENP RKM LEHHHHH H
Safety Data Sheet
SDS
Usage
Mabioway's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
