Name
DUSP13 Human
Cat. No.
MAG-3582
Tag/Conjugates
His
Source
E.coli.
Shipped
Shipped with Ice Packs
Description
DUSP13 Human Recombinant produced in E. coli is a single polypeptide chain containing 222 amino acids (1-198) and having a molecular mass of 24.7kDa. DUSP13 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Introduction
Dual specificity phosphatase 13 (DUSP13) is a member of the protein-tyrosine phosphatase family. DUSP13 cooperates with protein kinases to control cell proliferation and differentiation. DUSP13 is engaged in the regulation of meiosis and/or differentiation of testicular germ cells in the course of spermatogenesis. DUSP13 demonstrates intrinsic phosphatase activity towards both phospho-seryl/threonyl and -tyrosyl residues of myelin basic protein, with similar specific activities in vitro.
Purification Method
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Physical Appearance
Sterile Filtered colorless solution.
Formulation
The DUSP13 solution (0.5mg/ml) contains 20mM Tris-HCl buffer, pH8.0, 20% glycerol, 1mM DTT and 0.1M NaCl.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Purity
Greater than 95% as determined by SDS-PAGE.
Biological Activity
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Safety Data Sheet
SDS
Usage
Mabioway's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Synonyms
Dual specificity protein phosphatase 13, Dual specificity phosphatase SKRP4, Testis- and skeletal-muscle-specific DSP, DUSP13, TMDP, BEDP, MDSP, SKRP4, DUSP13A, DUSP13B.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGSH MDSLQK QDLRRPKIHG AVQASPYQPP TLASLQRLLW VRQAATLNHI DEVWPSLFLG DAYAARDKSK LIQLGITHVV NAAAGKFQVD TGAKFYRGMS LEYYGIEADD NPFFDLSVYF LPVARYIRAA LSVPQGRVLV HCAMGVSRSA TLVLAFLMIC ENMTLVEAIQ TVQAHRNICP NSGFLRQLQV LDNRLGRETG RF.
Background
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