Cat. No.
MABL-019
Application
IP, WB, ELISA, FC
Isotype
Engineer antibody
Species Reactivity
Rat, Human, Mouse
Clone No.
M5
From
Recombinant Antibody
Specificity
The antibody binds to human and rat NgR1 with a Kd of 2.9 nM for both species (bivalent binding).
Alternative Names
Nogo-66 Receptor
UniProt
Q86UN2
Immunogen
(His)6-tagged fragment of rat NgR1 (amino acids 278-473).
Application Notes
The antibody binds specifically to residues 379-448 of NgR1, a member of the Nogo- 66 receptor family which inhibits axonal growth and sporulating in the CNS.
Antibody First Published
Hofer et al. Chimeric Rabbit/Human Fab and IgG Specific for Members of the Nogo-66 Receptor Family Selected for Species Cross-Reactivity with an improved Phage Display Vector.
Journal of Immunological Methods 2008; 318(1-2):75-87 PMID:17140598
Note on publication
Describes the generation of two monoclonal rabbit antibodies against members of the Nogo-66 receptor family.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
