Cat. No.
MABL-021
Application
WB, ELISA
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
B2212A
From
Recombinant Antibody
Specificity
The antibody binds specifically to the fn3-fibronectin domain of Human ROBO-1.
Alternative Names
Roundabout-1
UniProt
Q9Y6N7
Immunogen
Human recombinant ROBO-1.
Application Notes
This antibody binds to human ROBO-1, a receptor for SLIT1 and SLIT2. ROBO-1 is involved in axonal navigation, lung development, and cell migration.
Antibody First Published
Ito et al. Identification of ROBO1 as a novel hepatocellular carcinoma antigen and a potential therapeutic and diagnostic target. Clinical Cancer Research 2006; 12(11 Pt 1):3257- 64 PMID:16740745
Note on publication
Describes the generation of monoclonal antibodies against new cell surface targets for treatment of heptacellular carcinomas.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
