Cat. No.
MABL-063
Application
lateral flow immunoassay, LFA, ELISA
Isotype
Engineer antibody
Species Reactivity
Species independent
Clone No.
THC
From
Recombinant Antibody
Specificity
This antibody specifically recognizes parent THC (Δ9-THC) and its derivatives. THC is the main psychoactive substance present in cannabis (marijuana). THC acts on cannabinoid receptors in the central nervous system (also present in the immune system), and their activation brings about its psychoactive effects.
Alternative Names
Δ9-THC; tetrahydrocannabinol; Δ⁹-tetrahydrocannabinol; (−)-trans-Δ⁹- tetrahydrocannabinol; cannabinol; cannabis; marijuana; delta-9-tetrahydrocannabinol
UniProt
Immunogen
The original antibody was generated by immunizing New Zealand White rabbits with a THC- KLH conjugate.
Application Notes
This antibody presented a superior sensitivity towards parent THC (Δ9-THC) and its metabolites in comparison with many other anti-THC antibodies tested in ELISA and lateral flow immunoassay. As a result, this antibody might be used in THC detection methods from saliva samples, which would be a preferable, easy way of substance-abuse screening. It can also be potentially utilized in the clinic to treat THC overdose (US7749772B1).
Antibody First Published
Wang, Antibody and immunoassays for determining the presence of Δ9- Tetrahydrocannabinol. Wang, D. (2010). U.S. Patent No. 7,749,772. Washington, DC: U.S. Patent and Trademark Office. PMID:
Note on publication
The original publication describes the generation and characterization of this anti- THC antibody.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
