Cat. No.
MABL-080
Application
IB, IHC
Isotype
Engineer antibody
Species Reactivity
Rat, Xenopus, Human, Mouse
Clone No.
K75/41
From
Recombinant Antibody
Specificity
This antibody is specific for Kv4.3. It does not cross-react with Kv4.2.
Alternative Names
K75/41R; Potassium voltage-gated channel subfamily D member 3; Kcnd3
UniProt
Q62897
Immunogen
This antibody was raised by immunising BALB/c mice with a fusion protein consisting of the cytoplasmic C-terminus (amino acids 415-636) of rat Kv4.3.
Application Notes
The specificity of this antibody has been confirmed in immunohistochemical analysis; while this antibody stains adult rat hippocampus sections (Andrews et al, 2019; PMID:30667360), brain sections from Kv4.3−/− mice remain blank (Burkhalter et al, 2006). This antibody has been used in immunoblot analysis of rat, mouse and frog brain membranes (Andrews et al, 2019; PMID:30667360).Additionally, this antibody has been used to assess Kv4.3 expression in mouse primary visual and primary somatosensory cortex through immunofluorescence imaging (Burkhalter et al, 2006).
Antibody First Published
Burkhalter et al. Differential Expression of IA Channel Subunits Kv4.2 and Kv4.3 in Mouse Visual Cortical Neurons and Synapses Journal of Neuroscience 22 November 2006, 26 (47) 12274-12282 PMID:17122053
Note on publication
Describes the original use of this antibody.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
