Cat. No.
MABL-104
Application
ICC, WB, IHC
Isotype
Engineer antibody
Species Reactivity
Rat, Human, Mouse
Clone No.
N16B/8
From
Recombinant Antibody
Specificity
This antibody is specific for the Kv3.1b K+ channel. The Kv3.1b K+ channel is a voltage-gated potassium channel that plays an important role in the rapid repolarization of fast-firing brain neurons.
Alternative Names
N16B/8R; N16B/8; Potassium voltage-gated channel subfamily C member 1; Kcnc1; NGK2; RAW2; Voltage-gated potassium channel subunit Kv3.1; Voltage-gated potassium channel subunit Kv4
UniProt
P25122
Immunogen
This antibody was raised by immunising BALB/c mice with a fusion protein amino acids 437- 585 (cytoplasmic C-terminus) of rat Kv3.1b.
Application Notes
Western blot has been preformed on the brainstem of mice using this antibody (Dagley et al, 2014; PMID:24259518). This antibody has shown to be useful in the immunostaining of the mouse brain (Barry et al, 2013; PMID:23487040)
Antibody First Published
Andrews et al. A toolbox of IgG subclass-switched recombinant monoclonal antibodies for enhanced multiplex immunolabeling of brain eLife. 2019; 8: e43322. PMID:30667360
Note on publication
This article describes the generation of a library of recombinant monoclonal antibodies (R-mAbs) from a pool of mAb-producing hybridomas for neuroscience research.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
