Cat. No.
MABL-105
Application
ICC, WB
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
N170A/1.1
From
Recombinant Antibody
Specificity
This antibody is specific for neurexin-1-beta and shows no crossreactivity with neurexin-2- beta. Neurexin-1-beta is a neuronal cell surface protein that may be involved in cell recognition and cell adhesion by forming intracellular junctions through bindi
Alternative Names
N170A/1.1R; N170A/1; NRXN1; Neurexin I-beta
UniProt
P58400
Immunogen
This antibody was raised by immunising BALB/c mice with a synthetic peptide amino acids 47-64 (ASSLGAHHIHHFHGSSKH, extracellular N-terminus) of rat Neurexin-1-Beta.
Application Notes
This antibody is recommended for the detection and analysis of neurexin-1-beta by western blot and immunocytochemistry. For instance, the mouse version of this antibody was used to detect neurexin-1-beta by western blot in extracts of COS cells transiently transfected with Flag-tagged Neurexin-1-Alpha, Neurexin-1-Beta or untagged Kv2.1 plasmid.
Antibody First Published
Andrews et al. A toolbox of IgG subclass-switched recombinant monoclonal antibodies for enhanced multiplex immunolabeling of brain eLife. 2019; 8: e43322. PMID:30667360
Note on publication
This article describes the generation of a library of recombinant monoclonal antibodies (R-mAbs) from a pool of mAb-producing hybridomas for neuroscience research.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
