Cat. No.
MABL-112
Application
Isotype
Engineer antibody
Species Reactivity
Mouse
Clone No.
N2/16
From
Recombinant Antibody
Specificity
This antibody is specific for the Kcnu1 protein. Kcnu1 is a testis-specific potassium channel activated by both intracellular pH and membrane voltage that mediates export of K+.
Alternative Names
N2/16R; N2/16; Potassium channel subfamily U member 1; Calcium- activated potassium channel subunit alpha-3; Calcium-activated potassium channel, subfamily M subunit alpha-3; Pore-forming subunit of the sperm-specific alkalization activated K(+) current; KSper; Slowpoke homolog 3; mSlo3; pH-sensitive maxi potassium channel
UniProt
O54982
Immunogen
This antibody was raised by immunising BALB/c mice with a fusion protein amino acids 1052- 1121 of mouse Slo3.
Application Notes
This antibody was used to preform a western blot on mouse oocytes and the testis of SLo3 knockout mice (Yang et al, 2011; PMID:22084117) (Santi et al, 2010;PMID:20138882).
Immunopercipitation on mouse oocytes has been preformed with this antibody (Yang et al, 2011; PMID:22084117).
Antibody First Published
Santi et al. The SLO3 sperm-specific potassium channel plays a vital role in male fertility FEBS Lett. 2010 Mar 5;584(5):1041-6. PMID:20138882
Note on publication
This article describes the knockout of the SLo3 gene and the subsequent results on mouse fertility
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
