Cat. No.
MABL-113
Application
ICC, IP, WB, IF
Isotype
Engineer antibody
Species Reactivity
Rat, Human, Mouse
Clone No.
N205B/22
From
Recombinant Antibody
Specificity
This antibody is specific for the LRRTM4 protein, but it binds to both the short and long isoforms of the protein. LRRTM4 may play a role in the development and maintenance of the vertebrate nervous system.
Alternative Names
N205B/22R; Leucine-rich repeat transmembrane neuronal protein 4
UniProt
Q86VH4
Immunogen
This antibody was raised by immunising BALB/c mice with a synthetic peptide amino acids 470-484 (ARESERQMNSPLQEY, cytoplasmic C-terminus) of human LRRTM4.
Application Notes
This antibody was used to preform an immunopercipitation on lysate from mouse retinas (Sinha et al, 2020; PMID:31974009). Western blot was preformed on proteins from mouse retinas using this antibody (Sinha et al, 2020; PMID:31974009). This antibody was used for immunocytochemistry on mouse neurons (de Wit et al, 2013; PMID:23911103). Immunofluorescense was preformed on the eyecups and lenses of C57BL mice using this antibody (Agosto and Wensel, 2020; PMID:32390181).
Antibody First Published
de Wit et al. Unbiased discovery of glypican as a receptor for LRRTM4 in regulating excitatory synapse development Neuron. 2013 Aug 21;79(4):696-711. PMID:23911103
Note on publication
This article describes research on the ligand-receptor interactions of the LRRTM4 protein
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
