Cat. No.
MABL-119
Application
WB
Isotype
Engineer antibody
Species Reactivity
Rat, Human, Mouse
Clone No.
N235/22
From
Recombinant Antibody
Specificity
This antibody is specific for pan-FHF-A. It cross-reacts with FGF12A/FHF1A and FGF14A/FHF4A, but does not cross-react with FGF13B/FHF2B. Pan-FHF-A is a microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules (By similarity).
Alternative Names
N235/22R; Fibroblast growth factor 13; FGF13; Fibroblast growth factor homologous factor 2; FHF-2
UniProt
Q92913
Immunogen
This antibody was raised by immunising BALB/c mice with a synthetic peptide amino acids 2- 18 (AAAIASSLIRQKRQARE) of human FHF2A.
Application Notes
This antibody has been used in immunocytochemistry experiments on DRG neurons from rats (Barbosa et al, 2016; PMID:27999940).
Antibody First Published
Barbosa et al FHF2 isoforms differentially regulate Nav1.6 mediated resurgent sodium currents in dorsal root ganglion neurons Pflugers Arch. 2017 Feb;469(2):195-212. PMID:27999940
Note on publication
This article describes the use of this antibody is research on the neurons of rats.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
