Cat. No.
MABL-156
Application
WB
Isotype
Engineer antibody
Species Reactivity
Rat, Human, Mouse
Clone No.
N81/37.1
From
Recombinant Antibody
Specificity
This antibody is specific for amino acids 861-912 of rat GABABR2. It shows no cross-reactivity against GABABR1. GABABR2 is a component of a heterodimeric G-protein coupled receptor for GABA, formed by GABBR1 and GABBR2.
Alternative Names
N81/37.1R; Gamma-aminobutyric acid type B receptor subunit 2; Gabbr2; GABA-B receptor 2; GABA-B-R2; GABA-BR2; GABABR2; Gb2; G-protein coupled receptor 51
UniProt
O88871
Immunogen
This antibody was raised by immunising BALB/c mice with fusion protein amino acids 861- 912 of rat GABABR2.
Application Notes
This antibody has been used for a western blot on a protein sample in mice where S783 was mutated to alanine (S783A) (Terunuma et al, 2014; PMID:24431439).
Antibody First Published
Terunuma et al. Postsynaptic GABAB receptor activity regulates excitatory neuronal architecture and spatial memory J Neurosci. 2014 Jan 15;34(3):804-16. PMID:24431439
Note on publication
Mice were created with enhanced postsynaptic GABABR signaling by mutating the serine 783 in receptor R2 subunit (S783A), which decreased GABABR degradation.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
