Cat. No.
MABL-161
Application
WB
Isotype
Engineer antibody
Species Reactivity
mouse ;rat, Human
Clone No.
N91/27.1
From
Recombinant Antibody
Specificity
This antibody is specific for amino acids 53-245 of human FGF13a. Cross-reacts with FGF13a and FGF13b does not cross-react with FGF11, FGF12 or FGF14 expressed in heterologous cells. FGF13a is a microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules.
Alternative Names
N91/27.1R; Fibroblast growth factor 13; FGF-13; Fibroblast growth factor homologous factor 2; FHF-2
UniProt
Q92913
Immunogen
This antibody was raised by immunising BALB/c mice with a fusion protein of amino acids 53- 245 of human FGF13a.
Application Notes
This antibody was used for western blot analysis on mouse ventricular NaV channel protein (Burel et al, 2017; PMID:28882890).
Antibody First Published
Burel et al. C-terminal phosphorylation of Na V 1.5 impairs FGF13- dependent regulation of channel inactivation J Biol Chem. 2017 Oct 20;292(42):17431-17448.PMID:28882890
Note on publication
Phosphoproteomic analyses to identify and quantify in situ the phosphorylation sites in the NaV1.5 proteins purified from adult WT and failing CaMKIIδc-overexpressing (CaMKIIδc-Tg) mouse ventricles was undertaken in this article.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
