Key features and details | |
Cat. No. | MABL-3164 |
Name | Anti-U3 and U8 RNP mAbs |
Clone No. | AFD- ASWA1 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | IP, ELISA |
Species Reactivity | Mouse |
Basic Information | |
Specificity | This antibody can recognize and bind U3, U8 ribonucleoprotein particles (RNP) and fibrillarin. |
Alternative Name | RNP; U3 ribonucleoprotein particle; U8 ribonucleoprotein particle; fibrillarin |
UniProt | |
Immunogen | The original antibody was generated by injecting A.SW mice with mercury. |
Application Notes | This antibody is capable of immunoprecipitating U3 and U8 ribonucleoprotein particles (RNP) as well as fibrillarin. The binding characterization of this antibody was done using ELISA. (PMID: 8283044). |
Antibody First Published | Monestier et al. Molecular analysis of mercury-induced antinucleolar antibodies in H-2S mice. J Immunol. 1994 Jan 15;152(2):667-75. PMID:8283044 |
Note on publication | Describes the generation of antinuclear autoantibodies in mice after administration of mercury. |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |