Cat. No.
MABL-415
Application
Blocking, ELISA
Isotype
Engineer antibody
Species Reactivity
Anopheles stephensi
Clone No.
8H7
From
Recombinant Antibody
Specificity
This antibody binds specifically to the turn-region of AAPP.
Alternative Names
Ansg-1; AAPP
UniProt
Q7YT37
Immunogen
Recombinant AAPP.
Application Notes
This antibody binds specifically to Anopheles anti-platetelet protein (AAPP), which blocks platelet adhesion to collagen by binding directly to collagen and subsequently aggregating platelets. This antibody prevents AAPP binding to collagen.
Antibody First Published
Sugiyama et al. The crystal strucuture of the active doain of Anopheles anti-platelet protein, a powerful anti-coagulant, in complex with an antibody. Journal of Biological CHemistry 2015; 289(23):16303-16312 PMID:24764297
Note on publication
Describes the generation of an anti- anti-platelet protein antibody and subsequent crystallography.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
