Cat. No.
MABL-580
Application
WB, ELISA, IHC
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
20E 3
From
Recombinant Antibody
Specificity
The original antibody is specific for CA125. CA125 is thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. This antigen that is the basis for a widely used serum assay for the monitoring of patients with ovarian epithelial cancer.
Alternative Names
TA347; Mucin-16; MUC-16; Ovarian cancer-related tumor marker CA125; CA-125; Ovarian carcinoma antigen CA125; CGMCC NO 20773
UniProt
Q8WXI7
Immunogen
The original antibody was generated by immunizing mice with recombinant protein CA125.
Application Notes
The antibody 20E3 and the commercial antibody TA347 were used to stain ovarian slurry adenocarcinoma and ovarian mucous adenocarcinoma in immunohistochemistry. Results showed the antibody specificity is comparable to the commercial antibody. Further, the staining intensity of the antibody 20E3 was higher than the commercial antibody (CN113061186A).
Antibody First Published
Note on publication
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
