Cat. No.
MABL-1126
Application
FC, IHC
Isotype
Engineer antibody
Species Reactivity
Mouse
Clone No.
YTS 156.7.7
From
Recombinant Antibody
Specificity
The antibody recognises the B epitope of the mouse Lyt-3 (CD8) antigen. Has been used in CD8 subset depletion in vivo and flow cytometry studies.
Alternative Names
Lyt-3; T-cell surface glycoprotein CD8 beta chain; Lymphocyte antigen 3; T-cell membrane glycoprotein Ly-3; T-cell surface glycoprotein Lyt-3; CD8b; Cd8b; Cd8b1; Ly-3; Lyt-3; Lyt3
UniProt
P10300
Immunogen
Mouse CD8 (lyt-3).
Application Notes
This antibody recognizes murine CD8 beta.
Antibody First Published
Cobbold S, Martin G, Waldmann H. Monoclonal antibodies for the prevention of graft-versus-host disease and marrow graft rejection. The depletion of CD8 T cell subsets in vitro and in vivo. Transplantation. 1986 Sep;42(3):239-47. PMID:3529524
Note on publication
Describes the production of monoclonal antibody to lyt-3 (CD-8) and demonstrates its effectiveness in CD8 subset depletion in mice.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
