Cat. No.
MABL-1409
Application
proliferation, SPR, FC
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
H3L2
From
Recombinant Antibody
Specificity
The antibody is specific for DLL4.
Alternative Names
Delta4; Delta-like protein 4; Drosophila Delta homolog 4
UniProt
Q9NR61
Immunogen
The original antibody is a humanized version of the parental murine monoclonal antibody.
Application Notes
The antibody retained the high affinity of the parental murine antibody to human DLL4 antigen (KD = 2.26 pM), as measured by SPR experiments. The humanized antibody bound to the DLL4 antigen on the surface of HUVEC cells, as shown by flow cytometry. Further, the antibody could block the inhibitory effect of DLL4 on the proliferation of HUVEC cells (CN105384819B).
Antibody First Published
Note on publication
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
