Cat. No.
MABL-1551
Application
Biacore, ELISA
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
H1
From
Recombinant Antibody
Specificity
This antibody binds to human Factor VIII.
Alternative Names
anti-hemophilic factor;Factor 8; FVIII; AHF; Coagulation factor VIII
UniProt
P00451
Immunogen
2D-PAGE gel isolated human Factor VIII from lysate of human melanoma COLO-38 cells.
Application Notes
Factor VIII (FVIII) is an essential blood-clotting protein, also known as anti-hemophilic factor (AHF). In humans, factor VIII is encoded by the F8 gene. Defects in this gene results in hemophilia A, a recessive X-linked coagulation disorder.
Antibody First Published
Pini et al. Design and use of a phage display library. Human antibodies with subnanomolar affinity against a marker of angiogenesis eluted from a two-dimensional gel. J Biol Chem. 1998 Aug 21;273(34):21769-76. PMID:9705314
Note on publication
Describes generation, using phage display, of antibodies with subnanomolar affinity against markers of angiogenesis.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
