Cat. No.
MABL-1692
Application
SPR, ELISA
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
5611
From
Recombinant Antibody
Specificity
The antibody recognises ghrelin. The antibody binds to an epitope residing within amino acids 1-8 of desacyl ghrelin. Ghrelin is a hormone produced by enteroendocrine cells of the gastrointestinal tract, especially the stomach and is often called a "hunger hormone" because it increases the drive to eat.
Alternative Names
GHRL; MTLRP; Appetite-regulating hormone; Growth hormone secretagogue; Growth hormone-releasing peptide; Motilin-related peptide; Protein M46
UniProt
Q9UBU3
Immunogen
The original antibody was generated by immunizing C57B16 wild-type mice with human ghrelin acylated with n-octanoic acid at the His residue at position 9.
Application Notes
The specificity of the original format of the antibody was confirmed by ELISA analysis. The antibody preferentially binds to desacyl ghrelin compared to acylated ghrelin. The binding affinity of the Fab fragment to desacyl human ghrelin was measured by surface plasmon resonance (Kd= 0.138 nM) (US20090060920).
Antibody First Published
Note on publication
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
