Cat. No.
MABL-1919
Application
ADCC, FACS
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
053-051
From
Recombinant Antibody
Specificity
The antibody is specific for ICAM1. ICAM1 is transmembrane glycoprotein having seven binding sites of the N-bonding sugar chain. The molecular weight is 90 kDa. ICAM belongs to Ig-superfamily and is known to be mainly involved with adhesion of leukocyte. It also mediates T lymphocyte adhesion to an antigen presenting cell (APC) and is involved with the interaction between T cell and T cell or between T cell and B cell.
Alternative Names
CD54; ICAM-1; Intercellular adhesion molecule 1; Major group rhinovirus receptor
UniProt
P05362
Immunogen
The original antibody was isolated by panning a phage display library against ICAM1.
Application Notes
The antibody could detect ICAM1 in different cell lines (Liver cancer cell line HepG2, pulmonary adenocarcinoma cell line PC14) by FACS analysis. The IgG1 format of the antibody exhibited ADCC activity on NCI-H441, NCI-H1373 and HepG2 cell lines (US9388249B2).
Antibody First Published
Note on publication
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
