Cat. No.
MABL-1931
Application
Biacore, ELISA
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
A4
From
Recombinant Antibody
Specificity
This antibody binds to human Interferon gamma
Alternative Names
IFNG; Interferon gamma; Immune interferon ; IFN-gamma
UniProt
P01579
Immunogen
2D-PAGE gel isolated human IFN gamma from lysate of human melanoma COLO-38 cells.
Application Notes
The antibody binds specifically to IFN gamma, a dimerised soluble cytokine member of the type II class of interferons synthesised by activated T-lymphocytes and natural killer (NK) cells. . IFNγ plays a role in both the innate and adaptive immune responses, and is important in the activation of macrophages, induces the expression of MHC class I molecules, and has antiviral and immunoregulatory activities.
Antibody First Published
Pini et al. Design and use of a phage display library. Human antibodies with subnanomolar affinity against a marker of angiogenesis eluted from a two-dimensional gel. J Biol Chem. 1998 Aug 21;273(34):21769-76. PMID:9705314
Note on publication
Describes generation, using phage display, of antibodies with subnanomolar affinity against markers of angiogenesis.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
