Cat. No.
MABL-2115
Application
FC
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
HC2
From
Recombinant Antibody
Specificity
HC2 recognizes human C-X-C chemokine receptor type 2, (CXCR2). CD182 is a 360 amino acid multipass membrane glcycoprotein and is expressed by neutrophils and monocytes, as well as by some subsets of T cells and endothelial cells.
Alternative Names
CXCR-2; CD182; C-X-C chemokine receptor type 2; CXC-R2; CXCR-2; GRO/MGSA receptor; High affinity interleukin-8 receptor B; IL-8R B; IL-8 receptor type 2
UniProt
P25025
Immunogen
This antibody was raised by immunizing mice with human IL-8 (interleukin-8) receptor, type B.
Application Notes
This antibody can be used in the detection and analysis of IL-8RB via flow cytometry (Zahn et al., 1997).
Antibody First Published
Zahn et al. Chemoattractant receptors for interleukin-8 and C5a: expression on peripheral blood leukocytes and differential regulation on HL-60 and AML-193 cells by vitamin D3 and all- trans retinoic acid. Eur J Immunol. 1997 Apr;27(4):935-40. PMID:9130647
Note on publication
This article describes the generation and characterization of HC2 antibody.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
