Cat. No.
MABL-2119
Application
FACS, inhibition, SPR, ELISA
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
148C09
From
Recombinant Antibody
Specificity
This antibody is specific for human IL12RB1
Alternative Names
CD212; IL12RB1#30; IL-12R-beta-1; IL-12RB1; Interleukin-12 receptor subunit beta-1; L-12 receptor subunit beta-1; IL-12R subunit beta-1; IL-12 receptor beta component
UniProt
P42701
Immunogen
Application Notes
The binding of the original version of this antibody (VHH) to IL12RB1 was characterized in an SPR (KD 3.3 nM), ELISA (IC50 3.7 and 1.5 nM for IL-12 and IL-23, respectively), and FACS (EC50 1.3 nM). In its bi-specific constructs with Ab04387 (Anti-CD4 [3F11]), it served a functional role (US20220242958).
Antibody First Published
Note on publication
The original publication describes the construction and characterization of various bi- specific antibodies.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
