Cat. No.
MABL-2126
Application
FC
Isotype
Engineer antibody
Species Reactivity
Mouse
Clone No.
5H4
From
Recombinant Antibody
Specificity
This antibody is specific for the murine interleukin-2 receptor beta chain.
Alternative Names
CD122; IL-2Rβ; IL-2 receptor subunit beta; Interleukin-2 receptor subunit beta; High affinity IL-2 receptor subunit beta; p70-75
UniProt
P16297
Immunogen
This antibody was raised by immunising Lewis rats with transfected rat myeloma cell line YB2/0, expressing truncated murine IL-2R beta.
Application Notes
This antibody has been used in flow cytometric analysis of IL-2R beta expression by thymocytes, lymph node cells and 3B4.15 T hybridoma cells (Ligons et al, 2012), as well as NK cells (He et al, 1996; Frenkel et al, 2016; Put et al, 2016; Elkabets et al, 2009).
Antibody First Published
Malek et al. Biochemical Identity and Characterization of the Mouse Interleukin-2 Receptor β and γc Subunits. J Interferon Cytokine Res. 1995 May;15(5):447-54. PMID:7648447
Note on publication
Describes the original generation of this antibody, and its use in characterising the murine IL-2 receptor.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
