Cat. No.
MABL-2365
Application
FACS
Isotype
Engineer antibody
Species Reactivity
Mouse
Clone No.
DC8
From
Recombinant Antibody
Specificity
The antibody is specific for MHC class II.
Alternative Names
VHHDC8; H2-Ab1; H2-iabeta; H-2 class II histocompatibility antigen A beta chain; MHC class II antigen A beta; MHC-II A beta
UniProt
P14483
Immunogen
Application Notes
The original format of the antibody stained splenocytes by FACS analysis. 18F labeled antibody was successfully used to detect lymphoid organs and reveal tumors in mice (Rashidian et al., 2015; PMID: 26630549). Texas Red-conjugated antibody was employed for staining of lymphoid organs (Rashidian et al., 2015; PMID: 26955657).
Antibody First Published
Rashidian et al. Enzyme-Mediated Modification of Single-Domain Antibodies for Imaging Modalities with Different Characteristics Angew Chem Int Ed Engl. 2016 Jan 11;55(2):528-533. doi: 10.1002/anie.201507596. Epub 2015 Dec 2. PMID:26630549
Note on publication
The original paper describes the generation and characterization of the antibody.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
