Cat. No.
MABL-2377
Application
Block
Isotype
Engineer antibody
Species Reactivity
Mouse
Clone No.
GH1002
From
Recombinant Antibody
Specificity
The antibody binds to the monoclonal antibody MK2-23 with an affinity of 25 nM.
Alternative Names
MK2-23 idiotype; anti-idiotypic monoclonal antibody MK2-23
UniProt
Immunogen
Monoclonal antibody MK2-23.
Application Notes
The antibody binds specifically to MK2-23, an idiotypic monoclonal antibody known to induce immunity in patients with malignant melanoma.
Antibody First Published
Ban N, Day J, Wang X, Ferrone S, McPherson A. Crystal structure of an anti- anti-idiotype shows it to be self-complementary. J Mol Biol. 1996 Feb 2;255(4):617-27. PMID:8568901
Note on publication
Describes the structural characterisation of the Fab fragment of the mouse anti-anti- idiotypic monoclonal antibody GH1002. Also describes the interaction between GH1002 and the anti- idiotypic monoclonal antibody MK2023.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
