Cat. No.
MABL-2590
Application
ELISA
Isotype
Engineer antibody
Species Reactivity
Clone No.
1C2
From
Recombinant Antibody
Specificity
This antibody is specific for paclitaxel, an anti-neoplastic agent derived from the Pacific yew.
Alternative Names
PT; PTX; Taxol; 7-Xylosylpaclitaxel; Taxol-7-xyloside; 7-xylosyltaxol
UniProt
Immunogen
This antibody was raised by immunising BALB/c mice with a solution of 7-xylosyltaxol conjugated to the carrier protein bovine serum albumin (XylTax–BSA).7-xylosyltaxol is a taxol (paclitaxel) derivative, which binds to tubulin and inhibits microtubule dis
Application Notes
The reactivity of this antibody for free and immobilised paclitaxel has been confirmed in ELISA analysis (Yusakul et al, 2018).
Antibody First Published
Yusakul et al. Different expression systems resulted in varied binding properties of anti‑paclitaxel single‑chain variable fragment antibody clone 1C2 J Nat Med (2018) 72:310–316 PMID:29027080
Note on publication
Describes the original generation of this antibody, and the derivation of an scFv with the same binding specificity.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
