Cat. No.
MABL-2907
Application
crystalisation, WB, ELISA
Isotype
Engineer antibody
Species Reactivity
Mouse
Clone No.
MAB1857
From
Recombinant Antibody
Specificity
Detects recombinant mouse (rm)Lipocalin-2 and does not cross-react with rhLipocalin-1 or rhLipocalin‑2 by ELISA or WB.
Alternative Names
24p3; 25 kDa alpha-2-microglobulin-related subunit of MMP-9; HNL; LCN2; lipocalin 2 (oncogene 24p3); lipocalin 2; Lipocalin-2; migration-stimulating factor inhibitor; MSFI; neutrophil gelatinase-associated lipocalin; NGAL; NGALlipocalin-2; Oncogene 24p3; p25; Siderocalin; 228418
UniProt
P11672
Immunogen
Recombinant mouse Lipocalin2/NGAL - Gln21Asn200.
Application Notes
This antibody binds to mouse siderocalin, can be used for western blots and, as an Fab fragment, has been co-crystallized with murine Scn. It is unclear whether or not the antibody is able to block the interaction between Scn and cell-surface receptors mediating endocytosis and subsequent apoptosis (Correnti et al. 2012).
Antibody First Published
Nairz M et al. 2008 Interferon-gamma limits the availability of iron for intramacrophage Salmonella typhimurium Eur J Immunol. 2008 Jul;38(7):1923-36. doi: 10.1002/eji.200738056. PMID:18581323
Note on publication
Describes how this antibody was used to detect siderocalin via immunoblotting.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
