Cat. No.
MABL-3021
Application
FC, IF
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
11F2
From
Recombinant Antibody
Specificity
This antibody is specific for the native human TCR delta and gamma chains. The T-cell receptor (TCR) is a molecule found on the surface of T cells, or T lymphocytes, that is responsible for recognizing fragments of antigen as peptides bound to major histocompatibility complex (MHC) molecules.
Alternative Names
T-cell surface glycoprotein CD3 delta chain; CD3D; T-cell receptor T3 delta chain; T-cell surface glycoprotein CD3 gamma chain; CD3G; T-cell receptor T3 gamma chain; CD3g
UniProt
P04234; P09693
Immunogen
The mouse version of this antibody was raised by immunizing BALB/c mice with Purified native human TCRg/d.
Application Notes
To investigate the differentiation stages of human cd T-cells in cryopreserved peripheral blood mononuclear cells, PBMCs were stained for flow cytometry using the mouse version of this antibody (Wistuba-Hamprecht et al, 2014; pmid:24756989). To investigate the role of
Antibody First Published
Breit et al. Site-specific deletions involving the tal-1 and sil genes are restricted to cells of the T cell receptor alpha/beta lineage: T cell receptor delta gene deletion mechanism affects multiple genes J Exp Med. 1993 Apr 1;177(4):965-77. PMID:8459224
Note on publication
To determine wether tal-1 deletions are mediated via the same deletion mechanism as TCR-delta gene deletions.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
