Cat. No.
MABL-3150
Application
ELISA
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
TSM1.3
From
Recombinant Antibody
Specificity
This antibody is specific for human thyroid stimulating hormone. Thyroid stimulating hormone is a pituitary hormone that stimulates the thyroid gland to produce thyroxine (T4), and then triiodothyronine (T3) which stimulates the metabolism of almost every tissue in the body. It is a glycoprotein hormone produced by thyrotrope cells in the anterior pituitary gland, which regulates the endocrine function of the thyroid.
Alternative Names
Thyroid stimulating hormone; CHEBI:81567
UniProt
Immunogen
The original antibody was generated by immunizing balb/c mice with human TSH.
Application Notes
The binding characterization of this antibody towards thyroid stimulating hormone was done using ELISA (Iba et al., 1995)
Antibody First Published
Iba et al. A new system for the expression of recombinant antibody in mammalian cells. Biotechnology Letters volume 17, pages135–138(1995).
Note on publication
Describes the generation of two plasmids to be used in the generation of a chimeric antibody containing variable regions derived from a mouse and constant regions derived from a human antibody chain.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
