Key features and details | |
Cat. No.: | MAB-1 |
Name | Anti-Thy1.1 |
Clone No.: | AFD-OX7 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | WB, IHC |
Species Reactivity | Rat, Mouse |
Basic Information | |
Specificity | Rat CD90, also known as Thy1.1, a GPI-anchored membrane protein containing a single V type Ig-like domain. |
Alternative Name(s) of Target | CD90; Thy-1 antigen; OX-7 UniProt Accession Number of Target Protein |
UniProt | P01830 |
Immunogen | Rat Thy- 1L+ antigen in complete Freund's adjuvant. |
Application Notes | This antibody binds to Thy1.1, which is allelically restricted between different host strains. Administration of OX7 leads to anti-Thy1 Glomerulonephritis. |
Antibody First Published in | Mason DW, Williams AF. The kinetics of antibody binding to membrane antigens in solution and at the cell surface. Biochem J. 1980 Apr 1;187(1):1-20. PMID:6967725 |
Note on publication | Describes the generation of the antibody, shows it recognised Thy1.1 (Thy-1) by immuno-blotting of cell lines including thymocytes, neuronal cells, stem cells, immature B cells and connective tissues. |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |