Key features and details | |
Cat. No. | MAB-2 |
Name | Anti-Neural/glial antigen 2 (NG2) |
Clone No. | AFD-9.2.27 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | IP, FC, IF |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody is specific for human neural/glial antigen 2. |
Alternative Name(s) of Target | CSPG4; melanoma chondroitin sulfate proteoglycan; MCSP; CSP |
UniProt | Q6UVK1 |
Immunogen | The original antibody was generated by immunizing Balb/c mice with a 4M urea extract derived from human melanoma cells (M14). |
Application Notes | This antibody binds to melanoma-associated chondroitin sulphate proteoglycan, which stabilises cell-substratum interactions during the early stages of melanoma spreading. |
Antibody First Published in | Morgan et al. Production and characterization of monoclonal antibody to a melanoma specific glycoprotein. Hybridoma. 1981;1(1):27-36. PMID:6208119 |
Note on publication | The original publication details the production and characterization of a monoclonal antibody which recognizes a 240K dalton glycoprotein specific to melanoma cells. |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |