Key features and details | |
Cat. No. | MABL-296 |
Name | Anti-17ß estradiol mAbs |
Clone No. | AFD- 57-2 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | IP, RIA, WB, ELISA |
Species Reactivity | n/a |
Basic Information | |
Specificity | The antibody binds to 17ß estradiol with an affinity (Kd) of 2 nM. |
Alternative Name | 17-beta-estradiol; E2; ethynyl estradiol; oestradiol |
UniProt | |
Immunogen | Human 17ß estradiol. |
Application Notes | The antibody binds specifically to 17β-estradiol, the most potent member of the family of estrogens, which plays a role in both reproductive and non-reproductive physiological processes. 17βestradiol is an important hormone during the pre-ovulatory phase of the menstrual cycle and in the prevention of osteoporosis in women. Monoclonal antibody directed against the hormone are used routinely in immunoassays to measure serum levels of 17β-estradiol. |
Antibody First Published | Pajunen M, Saviranta P, Jauria P, Karp M, Pettersson K, Mäntsälä P, Lovgren T. Cloning, sequencing, expression and characterization of three anti-estradiol-17β Fab fragments. Biochim Biophys Acta. 1997 Mar20;1351(1-2):192-202. PMID:9116033 |
Note on publication | Describes the sequencing of three high affinity anti-estradiol-17β monoclonal antibodies and the determination of their crystal structures. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
