Cat. No.
MABL-408
Application
Isotype
Engineer antibody
Species Reactivity
Rat, Human
Clone No.
KAA8
From
Recombinant Antibody
Specificity
Alternative Names
octapeptide hormone angiotensin II; AII
UniProt
P01019
Immunogen
Angiotensin II
Application Notes
Angiotensin II is a potent regulator of blood pressure, body fluid and electrolyte homeostasis. It acts directly on vascular smooth muscle as a potent vasoconstrictor, affects cardiac contractility and heart rate through its action on the sympathetic nervous system, and alters renal sodium and water absorption through its ability to stimulate the zona glomerulosa cells of the adrenal cortex to synthesize and secrete aldosterone.
Antibody First Published
Mitchell,T.J. and Reilly,T.M. Amino acid sequence determination of three monoclonal antibodies to angiotensin II Pept. Res. 3 (6), 277-281 (1990) PMID 2134072
Note on publication
Describes the generation of anti-antgiotensin II antibodies.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
